![]() In addition, patients that are believed to probably not have adrenal cancer after their workup, and those who opt out of biopsy or surgery, often still require long-term follow up with regular re-imaging and repeated hormone testing, with resultant radiation exposure and high health care costs. However, even the latter has both a high diagnostic false positive and false negative rate, and ultimately the tumor is often resected, often unnecessarily, while, on the other hand, the delays due to the diagnostic work might also compromise optimal care for those tumors that prove malignant. ![]() The sizeable group of patients with larger or denser tumors end up with an arduous workup that frequently includes additional imaging studies, hormonal testing, and biopsy. Unfortunately, CT imaging alone is very limited in its ability to distinguish benign from malignant adrenal tumors only very small and hypodense lesions can be easily dismissed as benign.
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